THE DEFINITIVE GUIDE TO ZSTK474

In vitro drug interaction studies have shown that mitoxantrone didn't inhibit CYP450 1A2, 2A6, 2C9, 2C19, 2D6, 2E1 and 3A4 across a broad focus selection. The results of in vitro induction studies are inconclusive, but counsel that mitoxantrone may be a weak inducer of CYP450 2E1 action. Pharmacokinetic reports from the interaction of mitoxantrone